Il2rb (Extracell. Dom.) Rat Monoclonal Antibody [Clone ID: 9E33]
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Specifications
Product Data | |
Clone Name | 9E33 |
Applications | WB |
Recommended Dilution | Western Blot: 1/500 - 1/1000. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2 |
Clonality | Monoclonal |
Immunogen | Recombinant protein of IL-2Rbeta extracellular domain. |
Specificity | This antibody detects IL-2Rbeta. |
Formulation | State: Purified State: Lyophilized purified Ig |
Reconstitution Method | Restore with 200µl sterile PBS and the final concentration is 500µg/ml. |
Purification | Protein A/G affinity chromatography |
Database Link | |
Background | IL2 Receptor beta (CD122) is a member of the immunoglobulin superfamily that forms the high affinity IL2 receptor with CD25 and CD132. This receptor chain, which is also shared by the IL15 receptor, is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL2 Receptor beta chain can combine with either the common gamma subunit (gamma c) alone or the gamma c subunit and the IL2 Receptor alpha subunit to generate intermediate or high affinity IL2 receptor complexes, respectively. CD122 levels can be upregulated by activation stimuli such as IL2. |
Synonyms | Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL2 Receptor beta, P70-75 |
Reference Data |
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