CD131 / CSF2RB (Extracell. Dom.) Rat Monoclonal Antibody [Clone ID: 42A7]

CAT#: DM3566P

CD131 / CSF2RB (Extracell. Dom.) rat monoclonal antibody, clone 42A7, Purified

Specifications

Product Data

• Clone Name: 42A7
• Applications: WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant protein of IL-3Rbeta extracellular domain.
• Specificity: This antibody detects Mouse IL-3 Rβ but not IL-3Rα in Western blotting.
• Formulation: PBS
  State: Purified
  State: Lyophilized (0.2 µm filtered) purified IgG fraction
  Stabilizer: None
• Reconstitution Method: Restore with 200 µl sterile PBS and the final concentration is 500 µg/ml.
• Purification: Protein A/G Affinity Chromatography
• Background: IL3R common beta chain (IL3RB)is a member of the Ig superfamily and a type I transmembrane glycoprotein. The common beta subunit associates with the specific alpha subunits of IL3 receptor, IL5 receptor and GMCSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response.
• Synonyms: IL3RB, IL5RB, GM-CSF-RB