Il4ra (Extracell. Dom.) Rat Monoclonal Antibody [Clone ID: 16F23]

CAT#: DM3567P

Il4ra (Extracell. Dom.) rat monoclonal antibody, clone 16F23, Purified

Specifications

Product Data

• Clone Name: 16F23
• Applications: WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant Mouse protein of IL-4R extracellular domain of IL-4R.
• Specificity: This antibody detects Mouse IL-4R. Other species not tested.
• Formulation: Sterile PBS
  State: Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore with 200 µl sterile PBS and the final concentration is 500 µg/ml.
• Purification: Affinity Chromatography on Protein A/G
• Database Link:
  Entrez Gene 16190 Mouse
• Background: The Interleukin-4 receptor is a complex consisting of two chains. One chain is the high affinity IL-4 binding (p140, a chain, CD 124) chain and the other chain is the gamma chain. The high affinity IL-4 binding chain belongs to the cytokine receptor superfamily. The cytoplasmic domain contains Ser/Pro-rich regions similar to those present in the IL-2 receptor and GM-CSF receptor ß-chains. The recombinant human IL-4 soluble receptor corresponds to the human IL-4 receptor extracellular domain. The recombinant, human IL-4 sR is a potent IL-4 antagonist. This antibody will block IL-4 binding to its receptor.
• Synonyms: Interleukin-4 receptor alpha chain, IL-4R-alpha, IL4RA, 582J2.1, IL4 Receptor alpha