Il9r (Extracell. Dom.) Rat Monoclonal Antibody [Clone ID: 12F43]

CAT#: DM3569P

Il9r (Extracell. Dom.) rat monoclonal antibody, clone 12F43, Aff - Purified

Specifications

Product Data

• Clone Name: 12F43
• Applications: WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant Mouse protein of IL-6R extracellular domain
• Specificity: This antibody detects Mouse IL-9R. Other species not tested.
• Formulation: Sterile PBS
  State: Aff - Purified
  State: Lyophilized (0.2 µm filtered) purified Ig fraction
  Stabilizer: None
• Reconstitution Method: Restore with 0.2 ml sterile PBS and the final concentration is 0.5 mg/ml.
• Purification: Protein A/G Affinity Chromatography
• Database Link:
  Entrez Gene 16199 Mouse
• Background: Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG. The interleukin 9 receptor is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53% amino acid sequence identity, contain 468 and 533 amino acid residues, respectively. A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in a variety of hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.
• Synonyms: Interleukin-9 receptor, IL-9R, IL-9 receptor
• Note: Protein RefSeq: NP_001127930.1
  mRNA RefSeq: NM_001134458.1