Il10ra (Extracell. Dom.) Hamster Monoclonal Antibody [Clone ID: 9E12]

CAT#: DM3570P

Il10ra (Extracell. Dom.) hamster monoclonal antibody, clone 9E12, Purified

Specifications

Product Data

• Clone Name: 9E12
• Applications: WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
• Reactivities: Mouse
• Host: Hamster
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant protein of IL-10Ralpha extracellular domain.
• Specificity: This antibody detects IL-10Ralpha.
• Formulation: State: Purified
  State: Lyophilized purified Ig
• Reconstitution Method: Restore with 200µl sterile PBS and the final concentration is 500µg/ml.
• Purification: Protein A/G affinity chromatography
• Database Link:
  Entrez Gene 16154 Mouse
• Background: Interleukin 10 binds specifically and with high affinity to cell-surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10.
• Synonyms: Interleukin-10 receptor alpha chain, IL-10R-A, IL10 Receptor alpha