Il17ra (Extracell. Dom.) Rat Monoclonal Antibody [Clone ID: 10B27]

CAT#: DM3573P

Il17ra (Extracell. Dom.) rat monoclonal antibody, clone 10B27, Purified

Specifications

Product Data

• Clone Name: 10B27
• Applications: WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant protein of IL-17R extracellular domain.
• Specificity: This antibody detects IL-17R. No cross activity to IL-17B R.
• Formulation: State: Purified
  State: Lyophilized purified Ig
• Reconstitution Method: Restore with 200µl sterile PBS and the final concentration is 500µg/ml.
• Purification: Protein A/G affinity chromatography
• Database Link:
  Entrez Gene 16172 Mouse
• Background: Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq]
• Synonyms: IL-17 receptor, IL17R, CDw217