IFNA11 / Interferon alpha-11 Rat Monoclonal Antibody [Clone ID: 7D19]

CAT#: DM3588P

IFNA11 / Interferon alpha-11 rat monoclonal antibody, clone 7D19, Purified

Specifications

Product Data

• Clone Name: 7D19
• Applications: WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant protein of Limitin
• Specificity: This antibody detects Limitin.
• Formulation: State: Purified
  State: Lyophilized purified Ig
• Reconstitution Method: Restore with 200µl sterile PBS and the final concentration is 500µg/ml.
• Purification: Protein A/G affinity chromatography
• Background: Produced by macrophages, IFN alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. The innate immune response mediated by cells such as natural killer (NK) cells is critical for the rapid containment of virus replication and spread during acute infection. Subtype 11 of the type I interferon (IFN) family greatly potentiates the antiviral activity of NK cells during retroviral infection. Treatment of mice with IFN-α11 during Friend retrovirus infection (FV) significantly reduces viral loads and resulted in long-term protection from virus-induced leukemia.
• Synonyms: Limitin, IFN-alpha 11