Ly6g Rat Monoclonal Antibody [Clone ID: 6D17]

CAT#: DM3589P

Ly6g rat monoclonal antibody, clone 6D17, Purified

Product Images

Figure 1. Ly6G Immunohistochemistry staining paraffin sections of Mouse kidney and spleen tissues from LPS exposed animals.

Specifications

Product Data

• Clone Name: 6D17
• Applications: FC, IHC
• Recommended Dilution: FACS analysis: 1/500-1/2000.
  Immunohistochemistry on Paraffin Sections: 1/100-1/400.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Cell lysates of Mouse Neutrophils.
  Hybridoma: Mouse myeloma fused with spleen cells from a Rat.
• Specificity: The Ly-6G antibody has been used to identify peripheral blood neutrophils and deplete granulocytes in vivo.
• Formulation: PBS without additives
  State: Purified
  State: Lyophilized (0.2 µm filtered) purified Ig fraction
• Reconstitution Method: Restore with 200 µl sterile PBS (final concentration = 500 µg/ml).
• Purification: Affinity Chromatography on Protein A/G
• Gene Name: lymphocyte antigen 6 complex, locus G
• Database Link:
  Entrez Gene 546644 Mouse
• Background: Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation. Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Gr-1+ cells have recently been implicated in the development of antitumor responses.
• Synonyms: Gr-1 Granulocyte marker