Tlr2 (Extracell. Dom.) Rat Monoclonal Antibody [Clone ID: 5B57]

CAT#: DM3601P

Tlr2 (Extracell. Dom.) rat monoclonal antibody, clone 5B57, Purified

Specifications

Product Data

• Clone Name: 5B57
• Applications: WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant TLR2 extracellular domain
• Specificity: This antibody detects of TLR2, but not TLR1.
• Formulation: State: Purified
  State: Lyophilized purified Ig
• Reconstitution Method: Restore with 200µl sterile PBS and the final concentration is 500µg/ml.
• Purification: Protein A/G affinity chromatography
• Gene Name: toll-like receptor 2
• Database Link:
  Entrez Gene 24088 Mouse
• Background: TLR2 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognise pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram positive bacteria and yeast via stimulation of NF kappaB.
• Synonyms: Toll-like receptor 2