Trem2 (Extracell. Dom.) Rat Monoclonal Antibody [Clone ID: 5J46]

CAT#: DM3603P

Trem2 (Extracell. Dom.) rat monoclonal antibody, clone 5J46, Purified

Specifications

Product Data

• Clone Name: 5J46
• Applications: WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Purified Mouse Recombinant TREM-2b extracellular domain
• Specificity: This antibody detects Mouse TREM-2b, but not TREM-1.
• Formulation: 0.2 μm filtered solution in PBS
  State: Purified
  State: Lyophilized purified (0.2 μm filtered) IgG fraction from Culture Supernatant
  Stabilizer: None
• Reconstitution Method: Restore with 200 µl sterile PBS and the final concentration is 0.5 mg/ml.
• Purification: Protein A/G Affinity Chromatography
• Gene Name: triggering receptor expressed on myeloid cells 2
• Database Link:
  Entrez Gene 83433 Mouse
• Background: TREM2 is a single Ig domain receptor expressed by cells of myeloid lineage. Two closely related transcripts were reported in mouse and designated TREM2a and TREM2b. TREM2 is a pattern recognition receptor that binds anionic ligands. It associates with the adapter protein DAP12 to deliver an activating signal that plays a role in both innate and adaptive immune responses.
• Synonyms: TREM-2b