BMP2 (+ BMP4) Rabbit Polyclonal Antibody

CAT#: DP3515

BMP2 (+ BMP4) rabbit polyclonal antibody, Purified


USD 300.00

2 Weeks*

Size
    • 200 ug

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Specifications

Product Data
Applications ELISA, IP, WB
Recommended Dilution ELISA: 2-5 µg/ml.
Immunoprecipitation: 1-5 µg/ml.
Western Blot: 1 µg/ml, it will detect 20 ng/lane of recombinant Human BMP-2/4-1 or BMP-2/4-2 under reducing conditions.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Highly purified Synthetic peptide C-terminal (20 amino acids) of Human BMP-2/4.
Specificity This polyclonal serum antibody DP3515 will detect Human BMP-2/4. 
The antibody displays cross-reaction with Human BMP-4 monomers in Western Blot.
Formulation PBS without preservatives
State: Purified
State: Lyophilized purified Ig fraction
Reconstitution Method Restore in sterile water to a concentration of 0.1-1.0 mg/ml. Centrifuge vial prior to opening.
Purification Protein A Chromatography
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens bone morphogenetic protein 2 (BMP2)
Background Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein with an apparent molecular weight of 26 kDa. BMP-2 regulates similarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. The amino acid sequence of recombinant human BMP-2 starts with MQAKHKQ (position 283) containing the Met from the E. coli expression vector.
Synonyms Bone morphogenetic protein 2, BMP-2, BMP-2A
Reference Data
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transmembrane
Protein Pathways Acute myeloid leukemia, Basal cell carcinoma, Cytokine-cytokine receptor interaction, Endocytosis, Hedgehog signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, TGF-beta signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.