Vegfa Rabbit Polyclonal Antibody

CAT#: DP3520B

Vegfa rabbit polyclonal antibody, Biotin, Aff - Purified


USD 310.00

2 Weeks*

Size
    • 50 ug

Product Images

Specifications

Product Data
Applications ELISA
Recommended Dilution ELISA: 1-10 µg/ml.
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Highly pure (> 95%) recombinant Murine VEGF164 Dimer derived from insect cells
Specificity The antibody recognizes VEGF-A.
Formulation PBS, pH 7.2
Label: Biotin
State: Aff - Purified
State: Lyophilized purified IgG fraction
Stabilizer: 50x BSA
Preservative: 0.02% Sodium Azide
Reconstitution Method Restore in sterile water to a concentration of 0.1-1.0 mg/ml. Centrifuge vial prior to opening.
Purification Antigen Affinity Chromatography
Conjugation Biotin
Background Mouse Vascular Endothelial Growth Factor164 (VEGF164), a 24 kDa protein consisting of 164 amino acid residues, is produced as a homodimer. VEGF164 is a polypeptide growth factor and a member of the platelet-derived growth factor family. It is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. Two high-affinity tyrosine kinase receptors for VEGF164 have been identified, VEGFR-1 (FLT-1), and VEGFR-2 (Flk-1). In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo and is also a chemoattractant for monocytes and endothelial cells. At least three different proteins are generated by differential splicing of the mouse VEGF gene: VEGF120, VEGF164 and VEGF188. The most abundant form is VEGF164. Whereas VEGF120 and VEGF164 are secreted proteins, VEGF188 is strongly cell-associated. In addition, the isoforms VEGF164 and VEGF188 bind to heparin with high affinity. A related protein of VEGF is placenta growth factor (PlGF) with about 53% homology and VEGF-B with similar biological activities.
Synonyms VEGFA, VEGF, VPF, Vascular endothelial growth factor A, Vascular permeability factor
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.