Estrogen Receptor 1 (ESR1) Rabbit Monoclonal Antibody [Clone ID: SP1]

CAT#: DRM001

Estrogen Receptor 1 (ESR1) rabbit monoclonal antibody, clone SP1, Supernatant


USD 2,125.00

3 Days*

Size
    • 500 ul

Product Images

Specifications

Product Data
Clone Name SP1
Applications IHC, WB
Recommended Dilution Immunohistochemistry on formalin-fixed paraffin embedded sections:
dilute 1:100 in an ABC method (30 minutes at room temperature).
Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
Recommended Positive Control: Breast Carcinoma
Reactivities Hamster, Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen Synthetic peptide derived from C-terminal of human estrogen receptor
Specificity This antibody recognizes a protein of 67kDa, which is identified as estrogen receptor (ER).
Cellular Localization: Nuclear.
Formulation State: Supernatant
State: Liquid tissue culture supernatant containing sodium azide as preservative
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background ER content of breast cancer tissue is an important parameter in the prediction of prognosis and response to endocrine therapy. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Synonyms ER alpha, Estradiol receptor, ESR1, ESR, NR3A1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.