CD23 Rabbit Monoclonal Antibody [Clone ID: SP23]
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Product Data | |
Clone Name | SP23 |
Applications | IHC |
Recommended Dilution | Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: Use at 1/100 dilution in an ABC method for 30 minutes at room temperature. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Tonsil. |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | Recombinant protein encoding Human CD23 48-248 aa |
Specificity | This antibody recognizes CD23. Cellular Localization: Cell membrane |
Formulation | State: Supernatant State: Liquid Tissue Culture Supernatant containing Sodium Azide as preservative. |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Background | CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma |
Synonyms | Fc-epsilon-RII, FCER2, CD23A, FCE2, IGEBF |
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