TAC1 Rabbit Polyclonal Antibody

CAT#: EUD551

TAC1 rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunofluorescence: 1/200-1/400
  (IF Microscopy using FITC with overnight incubation at 2-8°C).
  Immunohistochemistry on Paraffin Embedded and Frozen tissues: 1/400-1/800 (using PAP).
  Positive Control: Formalin-fixed paraffin sections of Rat colon.
• Reactivities: Fish, Human, Porcine, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Substance K / Neurokinin A (Peninsula) conjugated to BSA
• Specificity: This antibody reacts with Substance K / Neurokinin A.
  Absoprtion with 10-100 µg Substance K per ml diluted antiserum abolishes the staining,
  while Substance P does not.
• Formulation: State: Serum
  State: Lyophilized undiluted Serum.
• Reconstitution Method: Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.09% Sodium Azide.
• Storage: Prior to reconstitution store at 2-8°C.
  Following reconstitution store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens tachykinin precursor 1 (TAC1), transcript variant beta
• Database Link:
  Entrez Gene 24806 RatEntrez Gene 6863 Human
• Background: Neurokinin A/Substance K represents a member of the tachykinin family of peptides. Neurokinin A, which arises by cleavage of the substance P precursor, occurs in neurons in the central and peripheral nervous systems, and is particularly numerous in the gastrointestinal tract. The biological actions of neurokinin A are similar to those of substance P, and include vasodilation and stimulation of smooth muscle contraction.
• Synonyms: TAC1, NKA, NKNA, TAC2, Protachykinin-1, Substance K, Neuromedin L

Reference Data

• Protein Families: Druggable Genome, Secreted Protein