IL9 Rabbit Polyclonal Antibody

CAT#: PP1031P2

IL9 rabbit polyclonal antibody, Aff - Purified


USD 355.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Applications ELISA, FN, WB
Recommended Dilution Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of Human IL-9 (5.0 ng/ml), a concentration of 1.0-2.0 µg/ml of this antibody is required.
Sandwich ELISA: To detect Human IL-9 by Sandwich ELISA (using 100 µl/well antibody solution) a concentration of at least 0.5-2.0 µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated anti-Human IL9 antibody (PP1031B1 or PP1031B2) as a Detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human IL-9.
Western Blot: To detect hIL-9 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-9 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Highly pure (>98%), E.coli derived 14.0 kDa recombinant Human IL-9
Specificity This antibody detects Interleukin-9.
Formulation PBS, pH 7.2 without preservatives.
State: Aff - Purified
State: Lyophilized (sterile filtered) purified Ig fraction
Reconstitution Method Restore in sterile water to a concentration of 0.1-1.0 mg/ml.
Purification Affinity Chromatography.
Gene Name Homo sapiens interleukin 9 (IL9)
Background Interleukin 9 (IL9) is a cytokine preferentially produced by T helper type 2 lymphocytes and active on various cell types such as T and B lymphocytes, mast cells and haemopoietic progenitors; but no effect of this cytokine has been reported so far on mononuclear phagocytes. IL9 stimulates cell proliferation and prevents apoptosis. The IL9 receptor (IL 9R) belongs to the haemopoietic receptor superfamily and its signal transduction involves mainly the (JAK/STAT) pathway. Some studies have implicated IL9 as an important cytokine in a number of Th2 cytokine mediated pathologies, in particular asthma.
Synonyms IL-9, T-cell growth factor P40, P40 cytokine
Note Centrifuge vial prior to opening!
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Asthma, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.