Cd4 Rat Monoclonal Antibody [Clone ID: YTS191.1]
Specifications
Product Data | |
Clone Name | YTS191.1 |
Applications | FC, FN, IHC |
Recommended Dilution | Flow Cytometry: Use 10µl of 1/100-1/200 diluted antibody to label 10e6 cells in 100 µl. Immunohistochemistry on Frozen Sections. Functional asssays. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2b |
Clonality | Monoclonal |
Specificity | This antibody recognises the CD4 cell surface antigen, expressed by a subset of T lymphocytes. This clone exhibits depleting activity when used in vivo. |
Formulation | PBS, pH 7.4 without preservatives. State: Low Endotoxin State: Liquid purified IgG fraction. |
Concentration | 1.0 mg/ml |
Purification | Affinity chromatography on Protein G |
Database Link | |
Background | CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45 % of peripheral blood lymphocytes. It is also present on 80 % of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. |
Synonyms | T-cell surface antigen T4/Leu-3 |
Note | Endotoxin Level: less than 0.01 EU/µg |
Reference Data |
Documents
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