Cd4 Rat Monoclonal Antibody [Clone ID: YTS191.1]

CAT#: SM005P

Cd4 rat monoclonal antibody, clone YTS191.1, Purified

Product Images

Staining of mouse spleen with rat anti mouse CD4 antibody SM005P

Specifications

Product Data

• Clone Name: YTS191.1
• Applications: FC
• Recommended Dilution: Flow cytometry: 1/50 - 1/100; use 10 µl of the suggested working dilution to label 10e6 cells in 100 µl.
  Immunohistochemistry on frozen sections (3).
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity: This antibody recognises the murine CD4 cell surface antigen, expressed by a subset of T lymphocytes.
• Formulation: PBS, pH 7.4, containing 0.09% sodium azide
  State: Purified
  State: Liquid IgG fraction
• Concentration: 1.0 mg/ml
• Purification: Protein G affinity chromatography
• Database Link:
  Entrez Gene 12504 Mouse
• Background: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
• Synonyms: T-cell surface antigen T4/Leu-3
• Note: This clone exhibits depleting activity when used in vivo. We recommend the use of SM005LE for this purpose.