Cd4 Rat Monoclonal Antibody [Clone ID: YTS191.1]

CAT#: SM005P

Cd4 rat monoclonal antibody, clone YTS191.1, Purified


USD 475.00

5 Days*

Size
    • 250 ug

Product Images

Specifications

Product Data
Clone Name YTS191.1
Applications FC
Recommended Dilution Flow cytometry: 1/50 - 1/100; use 10 µl of the suggested working dilution to label 10e6 cells in 100 µl.
Immunohistochemistry on frozen sections (3).
Reactivities Mouse
Host Rat
Isotype IgG2b
Clonality Monoclonal
Specificity This antibody recognises the murine CD4 cell surface antigen, expressed by a subset of T lymphocytes.
Formulation PBS, pH 7.4, containing 0.09% sodium azide
State: Purified
State: Liquid IgG fraction
Concentration 1.0 mg/ml
Purification Protein G affinity chromatography
Background CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Synonyms T-cell surface antigen T4/Leu-3
Note This clone exhibits depleting activity when used in vivo. We recommend the use of SM005LE for this purpose.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.