Cd4 Rat Monoclonal Antibody [Clone ID: YTS191.1]
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Specifications
Product Data | |
Clone Name | YTS191.1 |
Applications | FC, IHC |
Recommended Dilution | Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 10e6 cells. Immunohistochemistry on Frozen Sections. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2b |
Clonality | Monoclonal |
Specificity | This antibody recognises the CD4 cell surface antigen, expressed by a subset of T-lymphocytes. This clone exhibits depleting activity when used in vivo (Antibody SM005LE is recommended for this purpose). |
Formulation | PBS, pH 7.4, with 0.09% sodium azide as preservative State: Purified State: Liquid purified IgG fraction. |
Concentration | 1.0 mg/ml |
Purification | Affinity chromatography on Protein G |
Database Link | |
Background | CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. |
Synonyms | T-cell surface antigen T4/Leu-3 |
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