Icam1 Hamster Monoclonal Antibody [Clone ID: 3E2B]

CAT#: SM010A

Icam1 hamster monoclonal antibody, clone 3E2B, Azide Free

Specifications

Product Data

• Clone Name: 3E2B
• Applications: ELISA, FC, FN, IHC
• Recommended Dilution: Flow cytometry: 50µg/ml, Use 5µl of the suggested working dilution to label 10e6 cells in 100µl.
  Immunohistochemistry on frozen sections.
  ELISA.
  Functional assays.
• Reactivities: Mouse
• Host: Hamster
• Isotype: IgG
• Clonality: Monoclonal
• Specificity: This antibody reacts with ICAM-1 (CD54) present on T-cells, B-cells, monocytes and endothelial cells.
• Formulation: Sterile filtered PBS
  State: Azide Free
  State: Liquid purified IgG
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography on Protein G
• Database Link:
  Entrez Gene 15894 Mouse
• Background: ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
• Synonyms: ICAM-1