Cd8a Rat Monoclonal Antibody [Clone ID: KT15]

CAT#: SM011APC

Cd8a rat monoclonal antibody, clone KT15, APC

Specifications

Product Data

• Clone Name: KT15
• Applications: FC
• Recommended Dilution: Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc recepto
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: T cell clone, C6. Spleen cells from a Spraque Dawley rat immunised with the C6 T cell clone were fused with cells of the NSO mouse myeloma cell line.
• Specificity: Mouse Ly2.1 and Ly2.2 cells. This antibody reacts with the CD8 alpha chain (non polymorphic).
• Formulation: PBS containing 0.09% Sodium Azide, 5% Sucrose and 1% Bovine Serum Albumin
  Label: APC
  State: Lyophilized purified IgG
  Label: Allophycocyanin
• Reconstitution Method: Restore with 1 ml distilled water
• Conjugation: APC
• Gene Name: Mus musculus CD8 antigen, alpha chain (Cd8a), transcript variant 1
• Database Link:
  Entrez Gene 12525 Mouse
• Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
• Synonyms: CD8 alpha chain, CD8A, MAL