Cd8a Rat Monoclonal Antibody [Clone ID: KT15]

CAT#: SM011PS

Cd8a rat monoclonal antibody, clone KT15, Purified


USD 340.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Clone Name KT15
Applications FC, IF, IHC
Recommended Dilution Immunofluorescence.
Flow Cytometry: Use 10 µl of 1/100-1/200 diluted antibody to label 10e6 cells in 100 µl.
Immunohistochemistry on Frozen Sections.
Reactivities Mouse
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen T cell clone, C6.
Specificity This antibody recognizes Ly2.1 and Ly2.2 cells; reacting with the CD8 alpha chain (non polymorphic). It is weakly cytotoxic.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative.
State: Purified
State: Liquid purified IgG fraction
Concentration 1.0 mg/ml
Purification Affinity Chromatography on Protein A
Gene Name Mus musculus CD8 antigen, alpha chain (Cd8a), transcript variant 1
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.