Msr1 Rat Monoclonal Antibody [Clone ID: 2F8]

CAT#: SM029R

Msr1 rat monoclonal antibody, clone 2F8, PE


USD 495.00

5 Days*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name 2F8
Applications FC
Recommended Dilution Flow cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Reactivities Mouse
Host Rat
Isotype IgG2b
Clonality Monoclonal
Immunogen RAW264 cell line. Spleen cells from immunised AO rats were fused with cells of the Y3 rat myeloma cell line.
Specificity This antibody recognises the murine scavenger receptor class A (SRA), type I and II, also known as CD204.
Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion.
Recent research shows that clone 2F8 recognises an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
Label: PE
State: Lyophilized purified IgG
Label: R. Phycoerythrin (RPE)
Reconstitution Method Restore with 1 ml distilled water.
Purification Affinity chromatography on Protein G
Conjugation PE
Background CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions.
Synonyms MSR1, SCARA1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.