Cd44 Mouse Monoclonal Antibody [Clone ID: 5035-41.1D]
Specifications
Product Data | |
Clone Name | 5035-41.1D |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells or 100 µl whole blood. |
Reactivities | Mouse |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Spleen cells from B6PL-Ly-2a / Ly-3a B6-Ly-1alpha mice. Spleen cells from immunised mice were fused with cells of the mouse P3-NS1-1-Ag4 myeloma cell line. |
Specificity | Ly24.2 found on more than 90% bone marrow cells and spleen cells, 56% of thymus cells and 90% of lymph node cells. This antibody recognises the following strains of mice:- C57BL/6, C57BL/10, C57/L, C58A, AKR, 129, SJL, NZB, C3H, CE, CBA/H. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: FITC State: Liquid purified IgG fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | 0.1 mg/ml |
Purification | Affinity chromatography on Protein G |
Conjugation | FITC |
Database Link | |
Background | CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. |
Synonyms | LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1 |
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