Tnfrsf4 Rat Monoclonal Antibody [Clone ID: OX-86]

CAT#: SM055FX

Tnfrsf4 rat monoclonal antibody, clone OX-86, FITC


USD 630.00

5 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name OX-86
Applications FC
Recommended Dilution Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Reactivities Mouse
Host Rat
Isotype IgG1
Clonality Monoclonal
Immunogen CHO cells transfected with murine OX40. Spleen cells from immunised AO rats were fused with cells of the mouse NS1 myeloma cell line.
Specificity This antibody recognises OX40 (CD134), a cell surface antigen expressed only by activated T lymphocytes.
Formulation PBS, pH7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
Label: FITC
State: Liquid purified IgG
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.5 mg/ml
Purification Affinity chromatography on Protein G
Conjugation FITC
Background The OX40 receptor is also known as CD134, ACT35, and tumour necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.
Synonyms TNFRSF4, TXGP1L, ACT35 antigen, OX40L receptor
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.