CD4 Mouse Monoclonal Antibody [Clone ID: RPA-T4]

CAT#: SM1058F

CD4 mouse monoclonal antibody, clone RPA-T4, FITC


USD 415.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name RPA-T4
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat-1/10 diluted antibody to label 106 cells or 100 µl of lysed whole peripheral blood.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human PHA blasts.
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI myeloma cell line.
Specificity This antibody recognizes CD4.
Epitope mapping studies have shown that antibodies, produced by clone RPA-T4, recognize an epitope within domain 1, of the extracellular region, of the CD4 molecule.
Clone RPA-T4 has been reported to block gp120-CD4 interaction and inhibit syncytium formation. We recommend the use of SM1058LE for this purpose.
Formulation PBS, pH 7.4
Label: FITC
State: Liquid purified IgG fraction from tissue culture supernatant
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Affinity Chromatography on Protein G
Conjugation FITC
Background CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Synonyms T-cell surface antigen T4/Leu-3
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.