CD8B Mouse Monoclonal Antibody [Clone ID: 2ST8.5H7]

CAT#: SM1064P

CD8B mouse monoclonal antibody, clone 2ST8.5H7, Purified

Specifications

Product Data

• Clone Name: 2ST8.5H7
• Applications: FC, IP, WB
• Recommended Dilution: Western Blot.
  Immunoprecipitation.
  Flow Cytometry: Use 10 µl of neat-1/10 diluted CD8b antibody to label 10e6 cells in 100 µl.
• Reactivities: Human, Monkey
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Normal Human T lymphocytes.
• Specificity: This antibody recognises the CD8 cell surface antigen.
  The antibody binds to the beta chain, recognising an epitope that is dependent upon expression of both CD8 alpha and CD8 beta.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 0.5% BSA as stabilizer.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 926 Human
• Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
• Synonyms: CD8B, CD8B1