CD42b / GPIbA Mouse Monoclonal Antibody [Clone ID: AK2]

CAT#: SM1105LE

CD42b / GPIbA mouse monoclonal antibody, clone AK2, Low Endotoxin

Specifications

Product Data

• Clone Name: AK2
• Applications: ELISA, FC, FN, IP
• Recommended Dilution: ELISA.
  Immunoprecipitation.
  Functional Assays.
  Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 100 µl whole blood.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antiboydy recognises the Human CD42b cell surface antigen, also known as platelet glycoprotein GP1B.
  Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets (Ref.1).
• Formulation: PBS, pH 7.2 without preservatives
  State: Low Endotoxin
  State: Liquid purified IgG fraction
  Stabilizer: None
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography on Protein G
• Background: CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF. CD42b is expressed by platelets and megakaryocytes.
• Synonyms: Platelet glycoprotein Ib alpha chain, Glycoprotein Ibalpha, GP-Ib alpha, GPIb-alpha