CD44 Mouse Monoclonal Antibody [Clone ID: VFF-7]

CAT#: SM1118F

CD44 mouse monoclonal antibody, clone VFF-7, FITC


USD 415.00

5 Days*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name VFF-7
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat antibody solution to label 10e6 cells in 100 µl.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of Human CD44.
Spleen cells from immunised BALB/c micewere fused with cells of the P3X63Ag8.653 myeloma cell line.
Specificity This antibody specifically recognises an epitope encoded by exon v6 on the variant portion of Human CD44.
Formulation Tris buffered saline containing 0.02% Sodium Azide as preservative and 1% BSA as stabilizer.
Label: FITC
State: Liquid purified IgG fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch
Background CD44 is the receptor for hyaluronic acid (HA). It mediates cell to cell and cell matrix interactions through its affinity for HA. Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. High protein heterogeneity due to several alternative splicing and post translational modification events. CD44R represents a heterogeneous group of CD44 variant isoforms expressed constitutively in epithelial cells and monocyte lineage cells and can be upregulated in activated leukocytes. CD44R, and in particular CD44v6 containing isoforms, may be involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to sites of inflammation. CD44v6 containing isoforms may be involved in tumor metastasis.
Synonyms CD44, LHR, MDU2, MDU3, MIC4, Phagocytic glycoprotein I, PGP-1, HUTCH-I, Extracellular matrix receptor-III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.