CD55 / DAF Mouse Monoclonal Antibody [Clone ID: 67]

CAT#: SM1141R

CD55 / DAF mouse monoclonal antibody, clone 67, PE


USD 495.00

5 Days*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name 67
Applications FC
Recommended Dilution Flow cytometry.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen K562 cells
Specificity This antibody reacts to CD55, also known as DAF.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Label: PE
State: Lyophilized purified IgG fraction.
Label: R. Phycoerythrin (RPE)
Reconstitution Method Restore with distilled water.
Purification Affinity chromatography on Protein G.
Conjugation PE
Background CD55 is the complement regulatory protein, decay accelerating factor (DAF). It is a 70kD glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. DAF carries the Cromer related blood group antigens. DAF has a wide distribution on cells in non-haemopoietic tissues, particularly epithelium and is specifically found at the foetal-maternal interface in placenta. Soluble forms of DAF are found, for example, in plasma, saliva and urine. The antigen on erythrocytes is pronase and chymotrypsin sensitive, but resistant to trypsin.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.