CD57 / HNK1 Mouse Monoclonal Antibody [Clone ID: TB01]

CAT#: SM1143F

CD57 / HNK1 mouse monoclonal antibody, clone TB01, FITC

Product Images

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD57:FITC (SM1143F).

Specifications

Product Data

• Clone Name: TB01
• Applications: FC
• Recommended Dilution: Flow cytometry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Human neuroblastoma cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3.X63.Ag8653 myeloma cell line.
• Specificity: This antibody recognises the CD57 molecule, expressed by NK cells and a subset of T cells.
• Formulation: PBS, pH7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
  Label: FITC
  State: Liquid purified IgG
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.1 mg/ml
• Purification: Ion exchange chromatography
• Conjugation: FITC
• Background: CD57 recognizes a (Mr 100-110kDa) oligosaccharide antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.
• Synonyms: HNK-1, LEU7, NK-1, NK-Cell marker, NK1