CD79A Mouse Monoclonal Antibody [Clone ID: ZL7-4]

CAT#: SM1161F

CD79A mouse monoclonal antibody, clone ZL7-4, FITC

Product Images

Staining of RAMOS cells with Mouse Anti Human CD79a-FITC.

Specifications

Product Data

• Clone Name: ZL7-4
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of neat antibody to label 1x10e6 cells in 100µl. We recommend incubation times of at least 30 minutes with this antibody.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: IgM complex isolated from Daudi cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
• Specificity: This antibody reacts with CD79a positive cells by flow cytometry.
  This clone has been reported to be useful in distinguishing B-CLL from mantle cell lymphoma in flow cytometric assays.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
  Label: FITC
  State: Liquid purified IgG fraction.
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Conjugation: FITC
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  This product is photosensitive and should be protected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 973 Human
• Background: A disulfide-linked heterodimer, consisting of CD79a / mb1 and CD79b / B29 polypeptides, is non-covalently associated with membrane bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. The CD79a/b heterodimer interacts with at least one tyrosine kinase (Lyn). Induction of tyrosine kinase activity after antigen binding causes phosphorylation of the CD79a/b dimer, and also of other molecules, thereby initiating intracellular signaling.
• Synonyms: IGA, MB1, B-Cell marker