CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: DF1513]

CAT#: SM1166LE

CD71 (TFRC) mouse monoclonal antibody, clone DF1513, Low Endotoxin

Specifications

Product Data

• Clone Name: DF1513
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of 1/10-1/25 diluted antibody to label 10e6 cells in 100 µl.
• Reactivities: Human, Monkey
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: KG1 cell line.
• Specificity: This antibody recognizes the CD71 cell surface antigen, a 190 kD homodimeric glycoprotein expressed by proliferating cells. CD71 acts as Receptor for Transferrin.
• Formulation: PBS without preservatives
  State: Low Endotoxin
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Storage: Store the antibody undiluted at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens transferrin receptor (TFRC), transcript variant 2
• Database Link:
  Entrez Gene 711568 MonkeyEntrez Gene 7037 Human
• Background: The transferrin receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein; it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin.The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease.
• Synonyms: TfR1, p90, Transferrin receptor protein 1
• Note: Low Endotoxin: < 0.01 EU/µg

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane
• Protein Pathways: Endocytosis, Hematopoietic cell lineage