CD105 (ENG) Mouse Monoclonal Antibody [Clone ID: SN6]

CAT#: SM1177FT

CD105 (ENG) mouse monoclonal antibody, clone SN6, FITC


USD 190.00

5 Days*

Size
    • 25 ug

Product Images

Specifications

Product Data
Clone Name SN6
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat antibody to label 106 cells in 100 µl.
Reactivities Equine, Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Partially purified cell membrane antigens from fresh leukaemia cells.
Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/NS1/1-Ag4-1 myeloma cell line
Specificity SM1177F recognizes the CD105 cell surface antigen.
Formulation PBS
Label: FITC
State: Liquid purified IgG fraction
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Purification Affinity Chromatography on Protein G from tissue culture supernatant.
Conjugation FITC
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name endoglin
Background CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
CD105 is a glycoprotein homodimer of 95 kD subunits.
CD105 is expressed by endothelial cells, activated monocytes and some leukaemia cells.
Synonyms ENG, END, HHT1, ORW, ORW1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.