IL3RA Mouse Monoclonal Antibody [Clone ID: 6H6]

CAT#: SM1190BT

IL3RA mouse monoclonal antibody, clone 6H6, Biotin


USD 270.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 6H6
Applications FC
Recommended Dilution Indirect immunofluorescence analysis by Flow cytometry.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
Specificity This antibody recognizes CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
Formulation Phosphate buffered saline (PBS)
Label: Biotin
State: Liquid purified Ig fraction
Preservative: 15 mM sodium azide, approx. pH 7.4
Label: Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Concentration lot specific
Conjugation Biotin
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Background CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
Synonyms Interleukin-3 receptor subunit alpha, IL-3R-alpha, IL3 receptor alpha
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.