IL3RA Mouse Monoclonal Antibody [Clone ID: 6H6]

CAT#: SM1190P

IL3RA mouse monoclonal antibody, clone 6H6, Purified


USD 220.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 6H6
Applications FC, IHC, IP, WB
Recommended Dilution Flow Cytometry.
Immunoprecipitation.
Western blot.
Immunohistochemistry on Frozen Sections.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
Specificity This antibody recognizes CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
Formulation Phosphate buffered saline (PBS)
State: Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration lot specific
Purification Affinity Chromatography on Protein A
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Background CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
Synonyms Interleukin-3 receptor subunit alpha, IL-3R-alpha, IL3 receptor alpha
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.