CTLA4 Mouse Monoclonal Antibody [Clone ID: BNI3]
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Specifications
Product Data | |
Clone Name | BNI3 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 20 µl of neat antibody to label 5x10e5 cells in 100 µl (Membrane permeabilisation is required). |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human CTLA-4/human IgG heavy chain fusion protein. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/X63-Ag8.653 myeloma cell line. |
Specificity | This antibody recognises the CD152 cell surface antigen, also known as CTLA-4 (cytotoxic T-lymphocyteassociated antigen 4). |
Formulation | PBS containing 0.09% Sodium Azide as preservative and 0.2% BSA as stabilizer. Label: PE State: Liquid purified IgG fraction. Label: R. Phycoerythrin (RPE) |
Purification | Affinity Chromatography |
Conjugation | PE |
Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD152 is a 45kD glycoprotein, expressed normally as a disulphide-linked homodimer. It is expressed transiently on the surface of T cells following activation (peaking at 3 days), but is often present within the cytoplasm. CD152 is a ligand for CD80 and CD86, and is important in cellular interactions during the immune response. |
Synonyms | CTLA-4 |
Reference Data |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.