HLA Class I ABC Mouse Monoclonal Antibody [Clone ID: W6/32]

CAT#: SM1222R

HLA Class I ABC mouse monoclonal antibody, clone W6/32, PE


USD 495.00

5 Days*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name W6/32
Applications FC
Recommended Dilution Flow Cytometry: Use 10 μl of neat antibody to label 1x106 cells or 100 μl whole blood.
This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.
Reactivities Bovine, Feline, Human, Monkey, Primate
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Purified human tonsil lymphocyte membranes.
Spleen cells from immunised BALB/c mice were fused with cells of the NS1/1 - Ag4.1 mouse myeloma cell line.
Specificity Antibody SM1222R recognises an antigenic determinant shared among products of the HLA A, B and C loci. Clone W6/32 recognises a conformational epitope, reacting with HLA class I alpha-3 and alpha-2 domains (See Ishitani, A. et al. for details).
MHC class I glycoproteins are found on the surface of almost all nucleated somatic cells.
Formulation PBS
Label: PE
State: Lyophilized purified IgG fraction from Tissue Culture Supernatant
Stabilizer: 1% BSA, 5% Sucrose
Preservative: 0.09% Sodium Azide
Label: R. Phycoerythrin (RPE)
Reconstitution Method Restore with 1ml distilled water
Purification Affinity Chromatography on Protein G
Conjugation PE
Background The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells.
Synonyms MHC class I ABC, HLA Class 2 ABC
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.