HLA Class II DP, DR, DQ Mouse Monoclonal Antibody [Clone ID: WR18]

CAT#: SM1225F

HLA Class II DP, DR, DQ mouse monoclonal antibody, clone WR18, FITC


USD 415.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name WR18
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of Neat-1/10 diluted antibody to label 10e6 cells or 100 µl whole blood.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human HLA Class II.
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS.0 myeloma cell line.
Specificity This antibody recognises a common determinant on the beta chain of Human MHC Class II, and stains cells expressing HLA-DR, DP and DQ.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilzer.
Label: FITC
State: Liquid purified IgG fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Affinity Chromatography on Protein G.
Conjugation FITC
Background The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II.
The antigen is expressed by B lymphocytes, monocytes and activated T lymphocytes.
Synonyms MHC class II antigen DP, DR, DQ, HLA class II histocompatibility antigen DP, DR, DQ
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.