T Cell Receptor (TCR) alpha/beta (alpha chain) Mouse Monoclonal Antibody [Clone ID: 3A8]

CAT#: SM1230PS

T Cell Receptor (TCR) alpha/beta (alpha chain) mouse monoclonal antibody, clone 3A8, Purified

Specifications

Product Data

• Clone Name: 3A8
• Applications: IHC, IP
• Recommended Dilution: Immunoprecipitation.
  Immunohistochemistry on Frozen Sections.
  Not suitable for Flow Cytometry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: This antibody reacts with the alpha chain constant region found on all alpha beta TCR bearing T-lymphocytes.
  It reacts with 92-98% of all CD3+ peripheral blood lymphocytes.
  Negative Species: Mouse, Rat.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Stabilizer: 0.5% BSA
  Preservative: 0.09% Sodium Azide
• Concentration: 0.1 mg/ml
• Purification: Affinity Chromatography on Protein A
• Background: TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR.
• Synonyms: TCRA, TCRB, T-Cell Receptor alpha, T-Cell Receptor beta, T-Cell Receptor alpha beta