HLAB (HLA-B) Mouse Monoclonal Antibody [Clone ID: BB7.1]

CAT#: SM1304F

HLAB (HLA-B) mouse monoclonal antibody, clone BB7.1, FITC


USD 415.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name BB7.1
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat-1/10 diluted antibody to label 1x106 cells in 100 µl whole blood.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Papain solubilized HLA-B7 antigen.
Specificity This antibody recognises the Human HLA-B7 antigen and does not cross-react with HLA-B27 or other related HLA antigens.
It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i.e. HLA-B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.
Formulation PBS, pH 7.4
Label: FITC
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation FITC
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. 
This product is photosensitive and should be protected from light.
Should this product contain a precipitate we recommend micro-centrifugation before use.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. 
The HLA B gene is part of the human HLA complex on chromosome 6 and there are a large number of variant alleles of this gene.
Synonyms HLAB, MHC class I antigen B7
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.