CD81 / TAPA1 Hamster Monoclonal Antibody [Clone ID: Eat2]
Specifications
| Product Data | |
| Clone Name | Eat2 |
| Applications | FC |
| Recommended Dilution | Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. |
| Reactivities | Mouse |
| Host | Hamster |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | 38C13, murine B cell line. Spleen cells from immunised Armenian hamsters were fused with cells of the mouse PX3-Ag.8.653 myeloma cell line. |
| Specificity | This antibody recognises and CD81. Eat 2 induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation. Eat 2 requires the presence of both extracellular loops of TAPA-1 for binding. |
| Formulation | PBS, pH 7.4, containing 1% BSA as stabilizer and 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified IgG fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
| Concentration | 0.1 mg/ml |
| Purification | Affinity Chromatography on Protein G. |
| Conjugation | FITC |
| Background | CD81 is a 26kD cell surface glycoprotein that is also known as TAPA-1. In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. |
| Reference Data | |
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