MUC2 Mouse Monoclonal Antibody [Clone ID: 996/1]

CAT#: SM1709

MUC2 mouse monoclonal antibody, clone 996/1, Purified

Specifications

Product Data

• Clone Name: 996/1
• Applications: FC, IHC, WB
• Recommended Dilution: Western Blot.
  Flow Cytometry (Membrane permeabilization is required).
  Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin Sections: This product does not require protein digestion pre-treatment of paraffin sections and does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
  Positive Control: Normal colon Tissue.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: MUC2 tandem repeat peptide.
  Spleen cells from immunised Balb/c mice were fused with cells of a mouse NSO myeloma cell line.
• Specificity: This antibody recognises the MUC2 mucin, and shows no cross-reactivity with MUC1, MUC3 or MUC4 mucins. In tissue sections SM1709 recognises colon, liver and prostate tissues strongly. The antibody recognises malignant colonic mucosa as well as normal mucosa.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography on Protein G
• Gene Name: mucin 2, oligomeric mucus/gel-forming
• Database Link:
  Entrez Gene 4583 Human
• Background: MUC2 expression is detected in such human tissues as normal colon, breast, prostate, salivary gland and in gastrointestinal, colonic, breast and prostate neoplasia. This antibody labels MUC2 in normal colon and colonic carcinomas where it produces intense perinuclear staining in goblet cells. It also reacts with normal and neoplastic breast tissues and with prostate adenocarcinoma.
• Synonyms: MUC-2, MUC2, SMUC, Intestinal mucin-2