Influenza A H3N2 (Matrix Protein M1) Mouse Monoclonal Antibody [Clone ID: GA2B]
CAT#: SM1748P
Influenza A H3N2 (Matrix Protein M1) mouse monoclonal antibody, clone GA2B, Purified
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Specifications
| Product Data | |
| Clone Name | GA2B |
| Applications | IF, WB |
| Recommended Dilution | Western Blot. Immunofluorescence: 1/100. |
| Reactivities | Human |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Influenza A / Puerto Rico / 8 / 34 (H1N1) and A/Bangkok / 1 / 79 (H3N2) viruses. Spleen cells from immunised BALB/c mice were fused with cells of the P3 Ag8.653 mouse myeloma cell line. |
| Specificity | This antibody recognises an epitope within the Influenza A matrix protein. This antibody can be used in influenza A IFA typing in conjunction with AM01375PU-N (clone AA5H). |
| Formulation | PBS, pH 7.5 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction (> 90% pure by SDS-PAGE). |
| Concentration | 1.0 mg/ml |
| Purification | Affinity Chromatography on Protein A. |
| Background | Influenza virus type A matrix protein, also known as M1, is composed of a 252 amino acid sequence and is type-specific in influenza viruses. It is located inside the viral lipid envelope and plays a key role in virus assembly and replication. M1 can be isolated from particles by removing the envelope with detergents and reducing the pH to 4.0. Influenza viruses are a common and widely spread infectious agent. Like many other viruses, influenza virus are constantly undergoing mutations and thereby avoiding the immune system. The Influenza A Virus M proteins form a continuous shell on the inner side of the lipid bilayer, maintaining the structural integrity of the virus particle through hydrophobic interactions. |
| Synonyms | Seasonal Flu H3N2 |
| Reference Data | |
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