CD36 Mouse Monoclonal Antibody [Clone ID: SM0]
Specifications
Product Data | |
Clone Name | SM0 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 10e6 cells in 100 µl. |
Reactivities | Human |
Host | Mouse |
Isotype | IgM |
Clonality | Monoclonal |
Immunogen | Human tonsil cells and peripheral blood mononuclear cells. Spleen cells from immunised mice were fused with cells of the NSI mouse myeloma line. |
Specificity | This antibody recognises the CD36 antigen. This antibody partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic neutrophils. This clone is also reported to block interaction of oxidised low-density lipoprotein (OXLDL) with CD36. We recommend the use of SM1769A for this purpose. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: FITC State: Liquid purified IgM fraction Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | lot specific |
Purification | Ammonium Sulphate Precipitation. |
Conjugation | FITC |
Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Gene Name | CD36 molecule |
Database Link | |
Background | CD36 is an 88kD cell surface glycoprotein expressed by platelets and monocytes/macrophages and also by some microvascular endothelium and erythroid precursors. CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. |
Synonyms | Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4 |
Reference Data |
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