CD2 Mouse Monoclonal Antibody [Clone ID: LT2]
Specifications
Product Data | |
Clone Name | LT2 |
Applications | FC, IHC, IP |
Recommended Dilution | Immunoprecipitation. Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 10e6 cells in 100 µl. Immunohistochemistry on Frozen Sections: 1/200-1/400. Recommended Positive Control Tissue: Human Tonsil. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Normal human peripheral blood lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line. |
Specificity | This antibody is a single chain transmembrane glycoprotein of 50kD. This antibody inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | CD2 molecule |
Database Link | |
Background | CD2 is expressed by T cells, NK cells and thymocytes. CD2 is a receptor for CD58 (LFA-3), and is important in mediating the interaction between T cells and target cells or antigen presenting cells. |
Synonyms | SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor |
Reference Data |
Documents
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