CD2 Mouse Monoclonal Antibody [Clone ID: LT2]

CAT#: SM1783R

CD2 mouse monoclonal antibody, clone LT2, PE

Product Images

Staining of human peripheral blood lymphocytes with Mouse Anti Human CD2-RPE (SM1783R/RT).

Specifications

Product Data

• Clone Name: LT2
• Applications: FC
• Recommended Dilution: Flow Cytometry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Normal human peripheral blood lymphocytes.
  Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line.
• Specificity: This antibody recognises the CD2 cell surface glycoprotein, a 50kD molecule expressed by T cells, NK cells and thymocytes.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative, 1% BSA as stabilizer and Inert Bulking Reagent.
  Label: PE
  State: Lyophilized purified IgG fraction.
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with 1 ml distilled water.
• Purification: Affinity Chromatography on Protein A
• Conjugation: PE
• Storage: Prior to and following reconstitution store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD2 molecule
• Database Link:
  Entrez Gene 914 Human
• Background: CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes.
  CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.
• Synonyms: SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor