CD8A Mouse Monoclonal Antibody [Clone ID: LT8]

CAT#: SM1784APCT

CD8A mouse monoclonal antibody, clone LT8, APC


USD 230.00

5 Days*

Size
    • 25 Tests

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Specifications

Product Data
Clone Name LT8
Applications FC
Recommended Dilution Flow Cytometry: Use 10 ul of neat antibody to label 10e6 cells or 100 ul human whole blood.
Reactivities Human, Monkey
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Normal human peripheral blood lymphocytes.
Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line.
Specificity This antibody recognises the alpha-chain of the CD8 antigen, a 32kD glycoprotein expressed by the cytotoxicsuppressor subset of T cells and weakly by NK cells.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Label: APC
State: Lyophilized purified IgG fraction.
Label: Allophycocyanin
Reconstitution Method Restore with 1 ml distilled water
Purification Ion Exchange Chromatography
Conjugation APC
Storage Prior to and following reconstitution store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens CD8a molecule (CD8A), transcript variant 1
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.