CD8A Mouse Monoclonal Antibody [Clone ID: LT8]
Other products for "CD8A"
Specifications
| Product Data | |
| Clone Name | LT8 |
| Applications | FC, IHC, IP |
| Recommended Dilution | Flow cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 10e6 cells or 100 µl human whole blood. Immunoprecipitation. Immunhistochemistry on Frozen Sections. |
| Reactivities | Human, Monkey |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Normal human peripheral blood lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line. |
| Specificity | This antibody recognises the alpha-chain of the CD8 antigen. |
| Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
| Concentration | lot specific |
| Purification | Ion Exchange Chromatography. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Gene Name | Homo sapiens CD8a molecule (CD8A), transcript variant 1 |
| Database Link | |
| Background | CD8 is a 32kD glycoprotein expressed by the cytotoxicsuppressor subset of T cells and weakly by NK cells. CD8 functions as a receptor for MHC Class I molecules. |
| Synonyms | CD8 alpha chain, CD8A, MAL |
| Reference Data | |
| Protein Families | Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane |
| Protein Pathways | Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway |
Documents
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