LOC105369261 Mouse Monoclonal Antibody [Clone ID: DFT-1]

CAT#: SM1793F

LOC105369261 mouse monoclonal antibody, clone DFT-1, FITC


USD 415.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name DFT-1
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat antibody to label 100 µl whole blood or 10e6 cells in 100 µl.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody recognizes the CD43. Clone DFT-1 binds to both glycoforms of human CD43 (Kyoizumi et al. 2004).
Formulation PBS
Label: FITC
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Affinity Chromatography on Protein G
Conjugation FITC
Background CD43 is one of the major glycoproteins of thymocytes and T lymphocytes, it plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response.
CD43 is expressed by the majority of leucocytes, with the exception of most B cells. However CD43 expression is seen in some cases of B cell lymphocytic lymphoma and centrocytic lymphoma.
Synonyms Leukocyte sialoglycoprotein, Sialophorin, Galactoglycoprotein, SPN
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.